Leaders in their fields, our scientists are deeply committed to the discovery and development of new medicines to address areas of serious need for patients. Leveraging our deep understanding of the biology of hemostasis gained over 15 years of research, we plan to accelerate the development of our innovative pipeline of programs in hemophilia, cold agglutinin disease, sickle cell disease, beta thalassemia, and other blood disorders.
Our pipeline includes hemophilia programs that have been designed to provide less-frequent prophylactic dosing for hemophilia A and subcutaneous dosing for hemophilia B, and gene therapy programs for hemophilia A and B.
It also includes programs to address cold agglutinin disease, a rare and chronic autoimmune hemolytic condition for which there are no approved therapies. Sutimlimab (formerly BIVV009) is the only therapy in development that is designed to selectively inhibit the classical complement pathway of the immune system. Sutimlimab targets C1s, thereby impacting the central mechanism of this disease.
We are also pursuing several approaches that seek to target the root cause of sickle cell disease, a profoundly debilitating disease that is linked to a shorter life expectancy and has few treatment options. Just as we have done in hemophilia, we hope to bring forward new medicines that meaningfully advance the treatment of people with sickle cell disease.